Mouse anti-PTEN , clone 6H2.1 (Monoclonal)

Clone Number: 6H2.1

Immunogen: C-terminal 100 aa of PTEN

Concentration: lot specific

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: PTEN gene is a tumor suppressor gene that maps to chromosome 10q23. PTEN, a novel tumor suppressor, functions as a regulator of both cell cycle progression and apoptosis ). Potentially, mutation and deletion of PTEN gene may result in a new signal transduction pathway related to human malignant tumors. Studies have demonstrated a reduction of PTEN expression in advanced breast cancers. Positive control tissue Breast, Renal Cell and Prostate carcinomas

References: Bose et al. Hum Path 2002;33(4):405-409/Bose et al. Mod Pathol 2006;19(2):238-245

• Artikelnummer: SANMON9985
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9985
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2a
• Wirt: Mouse