Mouse anti-Uroplakin III, clone AU1 (Monoclonal)

Clone Number: AU1

Immunogen: AUM preparation from bovine urinary bladder

Concentration: lot specific

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In non-neoplastic mammalian urothelium, UPs are expressed in the luminal surface plasmalemma of superficial (umbrella) cells, forming complexes of 16nm crystalline particles. UPIII is specific for tumors of urothelial origin and, when used in combination with other markers, can aid in the diagnosis of primary and metastatic tumors.

References: Moll et al. Am J Pathol 1995;147:1383-1397/Olsburgh et al. J Pathol 2003;199:41-49/Parket et al. 2003;27:1-10

• Artikelnummer: SANMON9989
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9989
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1
• Wirt: Mouse