Mouse anti-Vascular Endothelial Growth Factor (VEGF), clone VEGF-21 (Monoclonal)

Clone Number: VEGF-21

Immunogen: human VEGF189 recombinant protein

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: VEGF-21 reacts with Vascular Endothelial Growth Factor, also known as Vascular Permeability Factor (VEGF/ VPF) and is the key mediator of angiogenesis. The MWs are 19- 22kDa (reducing) and 38kDa-44kDa (non-reducing). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis. In addition to endothelial cells, VEGF and VEGF receptors are expressed on numerous non-endothelial cells including tumor cells.

References: Tischer E. et al. J. Biol. Chem 266: 11947-11954 (1991)/Berse B. et al, Mol. Biol. Cell 3: 211-220 (1992)/Folkman J. et al, Nature 339: 58-61 (1989)

• Artikelnummer: SANMON9844
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9844
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Rabbit, Dog (Canine)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Flow Cytometry
• Isotyp: IgG1-k
• Wirt: Mouse