Clone Number: LN-6
Immunogen: human thymic nuclear extract
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: LN-6 reacts with vimentin, a 58kDa protein, and specifically with a non-hematopoietic epitope of vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP) such as desmin, keratin, neurofilament, and glial fibrillary acid protein. Vimentin is ubiquitously expressed in mesenchymal cells such as fibroblasts, smooth muscle cells, and endothelium. Antibody against vimentin is useful as part of an antibody panel for differential diagnosis of tumors of unknown origin. It does not react with leukocyte common antigen-positive tissues such as lymphomas and leukemias.
References: Stathopoulos, E, et al, J. Histochem. Cytochem. 37: 1363-1370 (1989)