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Mouse anti Yeast (Saccharomyces cerevisiae) TUP1
Mouse anti Yeast (Saccharomyces cerevisiae) TUP1, Monoclonal, IgG, Clone: 10
Artikelnummer
EXAX1538M
Verpackungseinheit
100 µg
Hersteller
Exalpha Biologicals Inc
Verfügbarkeit:
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Clone: 10.
Background: Yeast Tup 1p-Ssn6p repressor complex represents a novel paradigm for transcriptional repression and for the role of chromatin in repression. TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation.
Positive Control: Mav108 cells expressing recombinant TUP1 protein.
Immunogen: Recombinant protein derived from the amino acids 1-200 of yeastt TUP1 protein.
Purification Method: Protein A/G Chromatography.
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.
References: 1. Bone, J.R. and Roth, S.Y. 'Recruitment of the yeast Tup1p-Ssn6p repressor is associated with localized decreases in histone acetylation.' J. Biol. Chem 2001, 276, 1808-1813
2. Watson, A.D., et al. 'Ssn6-Tup1 interacts with class I histone deacetylase required for repression.' Genes and Development 2000, 14, 2737-2744
3. Yang, X., et al. 'Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: Coupling protein O-GlcNAcylation to transcriptional repressor.' Cell 2002, 110, 69-80
4. DeSilva, H., et al. 'Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor.' Genetics 1998, 148, 657-667.
UniProt: P16649 (Yeast-Saccharomyces cerevisiae).
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Background: Yeast Tup 1p-Ssn6p repressor complex represents a novel paradigm for transcriptional repression and for the role of chromatin in repression. TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation.
Positive Control: Mav108 cells expressing recombinant TUP1 protein.
Immunogen: Recombinant protein derived from the amino acids 1-200 of yeastt TUP1 protein.
Purification Method: Protein A/G Chromatography.
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.
References: 1. Bone, J.R. and Roth, S.Y. 'Recruitment of the yeast Tup1p-Ssn6p repressor is associated with localized decreases in histone acetylation.' J. Biol. Chem 2001, 276, 1808-1813
2. Watson, A.D., et al. 'Ssn6-Tup1 interacts with class I histone deacetylase required for repression.' Genes and Development 2000, 14, 2737-2744
3. Yang, X., et al. 'Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: Coupling protein O-GlcNAcylation to transcriptional repressor.' Cell 2002, 110, 69-80
4. DeSilva, H., et al. 'Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor.' Genetics 1998, 148, 657-667.
UniProt: P16649 (Yeast-Saccharomyces cerevisiae).
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
| Artikelnummer | EXAX1538M |
|---|---|
| Hersteller | Exalpha Biologicals Inc |
| Hersteller Artikelnummer | X1538M |
| Green Labware | Nein |
| Verpackungseinheit | 100 µg |
| Mengeneinheit | STK |
| Reaktivität | Yeast |
| Klonalität | Monoclonal |
| Methode | Western Blotting |
| Isotyp | IgG |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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Gernot Ensinger, M.Sc.
