Mouse CTLA4:B7-1 TR-FRET Assay

Products from BPS Bioscience require a minimum order value above 400€

Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.

Description: The mouse CTLA4:B7-1 TR-FRET Assay is designed to measure the inhibition of mouse CTLA4 binding to mouse B7-1 in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing biotinylated mCTLA4, mB7-1 protein, anti-His Tb donor, dye-labeled acceptor, and an inhibitor is incubated for two hours. Then, the fluorescence intensity is measured using a fluorescence reader.

Storage Stability: At least 6 months from date of receipt when stored as directed.

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: Huxley, P., et al. Chem Biol. 2004 Dec;11(12):1651-8.

• Artikelnummer: BPS79508
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 79508
• Green Labware: Nein
• Verpackungseinheit: 384 rxns.
• Mengeneinheit: PAK