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MSH6 Polyclonal Antibody, Rabbit
MSH6 Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-92368-120
Verpackungseinheit
120 µl
Hersteller
Elabscience Biotechnology
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Abbreviation: MSH6
Target Synonym: MSH6; GTBP; GTMBP; HNPCC5; HSAP; p160; mutS homolog 6
Conjugation: Unconjugated
UNIProt ID: P52701
Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human MSH6
Dilution: WB 1:500-1:2000,IHC 1:50-1:100,IF 1:50-1:200
Target Synonym: MSH6; GTBP; GTMBP; HNPCC5; HSAP; p160; mutS homolog 6
Conjugation: Unconjugated
UNIProt ID: P52701
Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human MSH6
Dilution: WB 1:500-1:2000,IHC 1:50-1:100,IF 1:50-1:200
| Artikelnummer | ELSE-AB-92368-120 |
|---|---|
| Hersteller | Elabscience Biotechnology |
| Hersteller Artikelnummer | ELA-E-AB-92368-120 |
| Green Labware | Nein |
| Verpackungseinheit | 120 µl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus), Monkey (Primate) |
| Klonalität | Polyclonal |
| Methode | Immunofluorescence, Western Blotting, Immunohistochemistry |
| Isotyp | IgG |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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Gernot Ensinger, M.Sc.
Laurent Haze
