MYO3β, GST-tag Recombinant

Products from BPS Bioscience require a minimum order value above 400€

Encompassing Amino Acids: 1-326

Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 

Background: MYO3β is a member of the Class III myosins that are actin-dependent motor proteins containing an amino-terminal kinase domain. MYO3β contains an N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3β gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis shows expression of a 7-kb MYO3β transcript in the human retina but not in a RPE cell line (1). The MYO3β gene transcript is also detected in the kidney, intestine and testis. The MYO3β gene maps to chromosome 2q31.1-q31.2 by genomic sequence alignment.

Description: Recombinant Human MYO3β (a.a. 1-326), with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.

Format: Aqueous buffer solution

Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.

Genbank: NM_138995

Host Cell Line: Sf9 cells

Purity: ≥75%

Storage Stability: At least 6 months at -80°C.

Tags: N-terminal GST-tag

Uniprot: Q8WXR4

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: Dose, A C. et al: A class III myosin expressed in the retina is a potential candidate for Bardet-Biedl syndrome. Genomics 79: 621-624, 2002.

• Artikelnummer: BPS40137
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 40137
• Green Labware: Nein
• Verpackungseinheit: 10 µg
• Mengeneinheit: STK
• Wirt: Insect