Abbreviation: MYO7A
Target Synonym: MYO7A;DFNA11;DFNB2;MYOVIIA;MYU7A;NSRD2;USH1B
Conjugation: Unconjugated
UNIProt ID: Q13402
Background: This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human MYO7A
Dilution: WB 1:500-1:2000