N-Desethylamiodarone (hydrochloride), CAS 96027-74-6

Formulation: A crystalline solid

Formal Name: (2-butyl-3-benzofuranyl)[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]-methanone, monohydrochloride

Purity: ≥95%

Formula Markup: C23H25I2NO3 • HCl

Formula Weight: 653,7

Shelf life (days): 730

CAS Number: 96027-74-6

Notes: Amiodarone (Item No. 15213) is a class III antiarrhythmic agent, in that it prolongs both cardiac action potential and refractoriness by blocking potassium currents.{22478} It inhibits the voltage-gated potassium channel hERG, also known as KCNH2, with an IC50 value of 1 µM.{24593} In humans, cytochrome P450 3A is involved in the metabolism of amiodarone.{29074} N-Desethylamiodarone is the major, active metabolite of amiodarone. This compound has been used as an analytical reference standard for quantifying amiodarone in plasma samples.{29075}

• Artikelnummer: CAY9000537-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9000537-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe, Isotopenmarkierung