Formulation: A solid
Formal Name: (αS)-6-methoxy-α-methyl-2-naphthaleneacetic acid, monosodium salt
Purity: ≥95%
Formula Markup: C14H13O3 • Na
Formula Weight: 252,2
Shelf life (days): 1460
CAS Number: 26159-34-2
Notes: (+)-Naproxen is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor.{1791} It inhibits COX-1 and COX-2 in COS-1 cells expressing the human enzymes (IC50s = 4.8 and 28.4 µM, respectively). (+)-Naproxen inhibits thromboxane B2 (TXB2; Item No. 19030) and prostaglandin E2 (PGE2; Item No. 14010) production ex vivo in isolated rat blood (IC50s = 5 and 13 µM, respectively).{65387} Formulations containing (+)-naproxen have been used in the treatment of arthritis, osteoarthritis, gout, and ankylosing spondylitis.