Clone Name: GT1185
Application Note: WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. IP: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 60
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, 0.02% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot ID: Q04206
Antigen Species: Human
Immunogen: A synthesized peptide derived from human NF-κB p65.
Conjugation: Unconjugated
Full Name: RELA proto-oncogene, NF-kB subunit