Product Description: Nitro-PDS-Tubulysin M is a synthetic ADC drug-linker conjugate composed of the tubulin polymerization inhibitor Tubulysin M (an ADC Cytotoxin) and Nitro-PDS (an ADC linker).
Applications: Cancer-programmed cell death
Formula: C54H73N8O11S3
References: [1]FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1./[2]Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.
CAS Number: 1941168-69-9
Molecular Weight: 1106.40
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Drug-Linker Conjugates for ADC;Microtubule/Tubulin