NK1.1 / CD161c / Klrb1c, Mouse(PK136), 1mg/mL

Quote the promo code SZANTIBODY when ordering to receive a 10% discount on this antibody, from October 1st to December 31st 2024. No additional discounts during the promo.

Description: NK1. 1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by theKlrb1c/NKR-P1Cgene. It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes. NK1. 1 is expressed in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allograftsin vivo. NK-1. 1 has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. NK-1. 1 is commonly used as a mouse NK cell marker. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: PK136

Entrez Gene ID: 17059

Immunogen: CD Mouse spleen and bone marrow cells enriched for NK-1 cells

Expected AB Applications: Flow, surface (published for clone)/Functional studies (published for clone)

Z-Antibody Applications: Flow, surface (published)/Functional studies (published)

• Artikelnummer: BTMBNUM2010-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM2010-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Flow Cytometry, Functional Studies
• Isotyp: IgG2a kappa
• Wirt: Mouse
• Konjugat: Unconjugated