NOTCH1 antibody (GT1224)

Clone Name: GT1224

Application Note: WB: 1:500 - 1:2000. IP: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 273

Form: Liquid

Buffer (with preservative): PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.

Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]

Uniprot ID: P46531

Antigen Species: Human

Immunogen: A synthesized peptide derived from human Notch1

Purification: Purified by antigen-affinity chromatography

Conjugation: Unconjugated

Full Name: notch receptor 1

• Artikelnummer: GTX02821-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02821-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting
• Isotyp: IgG
• Human Gene ID: 4851
• Wirt: Rabbit