NPD-2975

Formulation: A solid

Formal Name: 5-(4-fluorophenyl)-3-isopropyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Purity: ≥98%

Formula Markup: C14H13FN4O

Formula Weight: 272,3

Shelf life (days): 730

Notes: NPD-2975 is an antiparasitic agent.{67501} It reduces the proliferation of T. brucei (IC50 = 63.1 nM) but not T. cruzi, L. infantum, P. falciparum, or human MRC-5 fibroblasts (IC50s = >6,000 nM for all). In vivo, NPD-2975 (50 mg/kg twice per day) reduces peripheral blood parasite levels below detection limits and increases survival in a mouse model of T. brucei infection.

• Artikelnummer: CAY39466-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39466-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK