Application Note: WB: 1:300-1:5000. IHC-P: 1:200-1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 44
Form: Liquid
Buffer (with preservative): 0.01M TBS, 1% BSA, 50% Glycerol, 0.03% Proclin300.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]
Uniprot ID: P25929
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide derived from human NPY1R (301-382).
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: neuropeptide Y receptor Y1