Notes: NT1-O14B is a tryptamine-containing ionizable cationic lipidoid.{68120} It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing NT1-O14B and the cationic lipidoid 306-O12B-3 (Item No. 37096) encapsulating antisense oligonucleotides (ASOs) against tau decreases tau brain levels in mice.