p38 MAPK Monoclonal Antibody (Clone 9F12)

Formulation: 200 µg of affinity-purified monoclonal antibody

Immunogen: human full length p38 MAPK

Clone Designation: 9F12

Shelf life (days): 1095

Notes: p38 mitogen-activated protein kinase (MAPK) is a member of the serine-threonine MAPK family that triggers many cellular processes including cell cycle, development, and apoptosis.{15420,15421} These kinases are activated by environmental stress signals such as osmotic shock, infection, and cytokines causing phosphorylation of p38 MAPK. This results in a phosphorylation cascade, activating transcription factors, and inducing gene expression.{15420,15424} p38 MAPK is widely expressed in heart, brain, skeletal muscle, platelets, and immune cells. Due to this distribution, p38 MAPK plays a role in cardiovascular disease, arthritis, and cancer.{15421,15422,1523,15424} It is mainly present in the cytosol, but can also be found in the nucleus after activation.{15421} Based on the amino acid sequence, the expected molecular weight of this protein is 41 kDa.

• Artikelnummer: CAY10011301-200
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10011301-200
• Green Labware: Nein
• Verpackungseinheit: 1 ea (200 µg)
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Western Blotting, Flow Cytometry, Immunocytochemistry
• Isotyp: IgG1
• Wirt: Mouse