PAMAM Dendrimer G5.5 Carboxylate (sodium salt) (water solution), CAS 202009-67-4

Formulation: A solution in water

Formula Markup: [NH2(CH2)2NH2]:(G=5.5);dendri PAMAM(NHCH2CH2COONa)256

Formula Weight: 52900,2

Shelf life (days): 730

CAS Number: 202009-67-4

Notes: PAMAM dendrimer G5.5 carboxylate (PAMAM G5.5 carboxylate) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini that has been used as a drug delivery system in vitro.{67596} It is approximately 103.9 Å in diameter in water and has 192 surface groups.{67554} Unlike PAMAM dendrimer G3.0 amine (Item No. 39073), PAMAM G5.5 carboxylate (100 µg/ml) does not induce cytotoxicity or autophagy in A549 cells.{51573} Bimetallic nanoparticles of PAMAM G5.5 carboxylate with gold and platinum scavenge DPPH (Item No. 14805) radicals in a cell-free assay.{51574} Complexes of PAMAM G5.5 carboxylate with the active component of cisplatin are cytotoxic to A2780 ovarian cancer cells (IC50 = 1.48 µM).{67596}

• Artikelnummer: CAY39110-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39110-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK