Formulation: A solid
Formal Name: (S)-4-((S)-2-((S)-1-(L-seryl-L-aspartyl-L-leucyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-5-(((S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl)amino)-5-oxopentanoic acid
Purity: ≥98%
Formula Markup: C38H53N9O13 • XCF3COOH
Formula Weight: 843,9
Shelf life (days): 1460
Notes: PapRIV is a quorum-sensing heptapeptide originally isolated from B. cereus.{69490} It is translated as a 48-amino acid polypeptide, which is secreted and extracellularly processed by NprB proteases to form the active heptapeptide.{69491} PapRIV (1-25 µM) induces IL-6 and TNF-α production by, and NF-κB translocation in, BV-2 microglia cells.{69490}