Parathyroid Hormone (1-34) (rat) (acetate)

Formulation: A solid

Formal Name: L-alanyl-L-valyl-L-seryl-L-α-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-alanyl-L-seryl-L-valyl-L-α-glutamyl-L-arginyl-L-methionyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-valyl-L-histidyl-L-asparaginyl-L-phenylalanine, acetate

Purity: ≥95%

Formula Markup: C180H291N55O48S2 • C2H4O2

Formula Weight: 4117,8

Shelf life (days): 1460

Notes: Parathyroid hormone (PTH) (1-34) is a synthetic N-terminal fragment of PTH that corresponds to amino acids 1-34 of mature PTH and a PTH receptor agonist.{69385,69386} It induces β-arrestin recruitment in HEK293H cells expressing human PTH receptor type 1 (PTH1R; EC50 = 7.7 nM) and adenylyl cyclase activation in COS-7 cells expressing rat PTH2R (EC50 = 0.41 nM). PTH (1-34) (100 nM) induces hypertrophy of primary rat ventricular cardiomyocytes.{69387} It increases tibial bone mineral density in ovariectomized rats when administered at a dose of 5 µg/kg.{29235}

• Artikelnummer: CAY36861-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36861-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe