PARP10/15-IN-3, CAS 2892064-88-7

Product Description: PARP10/15-IN-3 (Compound 8a) is a potent PARP10 and PARP15 dual inhibitor with IC50 values of 0.14 µM and 0.40 µM against PARP10 and PARP15, respectively. PARP10/15-IN-3 is able to enter cells and rescue cells from apoptosis[1].

Applications: Cancer-programmed cell death

Formula: C15H18N2O3

References: [1]Nizi MG, et al. Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15. Eur J Med Chem. 2022 Jul 5;237:114362.

CAS Number: 2892064-88-7

Molecular Weight: 274.32

Compound Purity: 99.98

Research Area: Cancer

Solubility: DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;PARP

• Artikelnummer: MEXHY-146502-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-146502-10.1
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK