PARP6, GST-Tag Recombinant

Products from BPS Bioscience require a minimum order value above 400€

Encompassing Amino Acids: full length

Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 

Assay Conditions: Enzyme reaction is conducted usingBPS's PARP6 Assay Kit (Catalog #80556) at room temperature for 1 hour.

Description: Human PARP6 (GenBank Accession No. NM_020214), full length with N-terminal GST-tag, MW = 98 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0,120 mM NaCl, 0.04% Tween-20, 16 mMglutathione, 20% glycerol, and 3 mM DTT.

Genbank: NM_020214

Storage Stability: At least 6 months at -80°C.

Tags: N-terminal GST-tag

Uniprot: Q2NL67

Unit Definition: One unit of PARP incorporates 100 pmoles of poly(ADP) in 1 minute from NAD into the acid-insoluble form.

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Ame,J.C., Spenlehauer,C. and de Murcia,G. Bioessays 26 (8), 882-893 (2004).
2. Hassa PO and Hottiger MO. Front Biosci. 1;13:3046-82 (2008). Application Reference(s):
Fragment-based ligand design of novel potent inhibitors of tankyrases (2013)

• Artikelnummer: BPS80506
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 80506
• Green Labware: Nein
• Verpackungseinheit: 10 µg
• Mengeneinheit: STK