PAX3 antibody, N-term

PAX3 antibody, N-term
Artikelnummer
GTX89743-100
Verpackungseinheit
100 μg
Hersteller
GeneTex

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Application Note: WB: 0.3-1μg/ml. IHC-P: 4.5μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 53

Positive Control: The peptide used to generate this antibody is available for purchase (GTX89743-PEP).

Specificity/Sensitivity: This antibody is expected to recognize all 8 reported isoforms (NP_852122.1; NP_000429.2; NP_039230.1; NP_852123.1; NP_852124.1; NP_852126.1; NP_852125.1; NP_001120838.1).

Form: Liquid

Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.

Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]

Uniprot ID: P23760

Antigen Species: Human

Immunogen: Peptide with sequence TTLAGAVPRMM-C, from the N Terminus of the protein sequence according to NP_852122.1; NP_000429.2; NP_039230.1; NP_852123.1; NP_852124.1; NP_852126.1; NP_852125.1; NP_001120838.1.

Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation: Unconjugated

Full Name: paired box 3
Mehr Informationen
Artikelnummer GTX89743-100
Hersteller GeneTex
Hersteller Artikelnummer GTX89743-100
Green Labware Nein
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Human
Klonalität Polyclonal
Methode Immunohistochemistry (paraffin), Western Blotting
Isotyp IgG
Human Gene ID 5077
Wirt Goat
Produktinformation (PDF) Download
MSDS (PDF) Download