Clone Name: ZR1
Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 48
Positive Control: Ovarian serous carcinoma
Specificity/Sensitivity: This antibody does not react with pancreatic neuroendocrine tumors, thymic tumors, and lymphocytes.
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Uniprot ID: Q06710
Antigen Species: Human
Immunogen: Synthetic peptide corresponding to the C-terminus of Human PAX8 protein
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: paired box 8