PCSK9 antibody (HL2666)

PCSK9 antibody (HL2666)
Artikelnummer
GTX639330-100
Verpackungseinheit
100 μl
Hersteller
GeneTex

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Clone Name: HL2666

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 74

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Uniprot ID: Q8NBP7

Antigen Species: Human

Immunogen: Recombinant fragment of human PCSK9.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: proprotein convertase subtilisin/kexin type 9
Mehr Informationen
Artikelnummer GTX639330-100
Hersteller GeneTex
Hersteller Artikelnummer GTX639330-100
Verpackungseinheit 100 μl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus)
Klonalität Recombinant
Methode Immunohistochemistry (paraffin), Western Blotting
Isotyp IgG
Human Gene ID 255738
Wirt Rabbit
Konjugat Unconjugated
Produktinformation (PDF) Download
MSDS (PDF)
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