PD-1:PD-L1 TR-FRET Assay

Products from BPS Bioscience require a minimum order value above 400€

Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.

Description: The PD-1:PD-L1 TR-FRET Assay is designed to measure the inhibition of PD-1 binding to PD-L1 in a homogeneous 96 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing europium-labeled (Eu) PD-1, dye-labeled acceptor, biotin-labeled PD-L1, and an inhibitor is incubated for two hours. Then, the fluorescence intensity is measured using a fluorescence reader.

Storage Stability: At least 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Molnar, E., et al. Proc Natl Acad Sci USA. 2008; 105: 10483-10488.2. Keir, M.E., et al. Annu. Rev. Immunol. 2008; 26: 677-704.

• Artikelnummer: BPS72032
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 72032
• Green Labware: Nein
• Verpackungseinheit: 96 rxns.
• Mengeneinheit: PAK