PD-L1 antibody (HL2293)

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Clone Name: HL2293

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 33

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis. [provided by RefSeq, Sep 2015]

Uniprot ID: Q9EP73

Antigen Species: Mouse

Immunogen: Synthetic peptide of mouse PD-L1

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: CD274 antigen

• Artikelnummer: GTX638348-S-25
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX638348-S-25
• Verpackungseinheit: 25 μl
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Recombinant
• Methode: Immunohistochemistry (paraffin), Western Blotting
• Isotyp: IgG
• Human Gene ID: 60533
• Wirt: Rabbit
• Konjugat: Unconjugated