PD-L2 (CD273), Fc fusion, Biotin-labeled (Human) Recombinant

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Encompassing Amino Acids: 20-219

Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function.

Assay Conditions: PD-1-PD-L2 binding activity, measuredusing the using the PD-1:PDL2[Biotinylated] Inhibitor Screening AssayKit, BPS Bioscience, Catalog #72004.

Description: Human secreted Programmed Death Ligand 2 (PD-L2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, fused at the C-terminus to the Fc portion of human IgG1, with C-terminal Avitag ™ expressed in a HEK293 cell expression system and enzymatically biotinlabeled using Avi-tag™ technology. MW = 51 kDa.

Format: Aqueous buffer solution

Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol

Genbank: NM_025239

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Fc fusion (Human IgG1), C-terminal Avi-tag™

Uniprot: Q9BQ51

Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.

Biosafety Level: Not applicable (BSL-1)

References: 1. Latchman, Y., et al., Nat. Immunol. 2001 Mar;2(3):261-8.
2. Saunders, P.A., et al., Eur. J. Immunol. 2005 Dec;35(12):3561-9.

• Artikelnummer: BPS71108
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71108
• Green Labware: Nein
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK