PE/Cyanine7 Anti-Mouse CD107a/LAMP-1 Antibody(1D4B), PE/Cy7, Rat, Monoclonal

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Swissprot: P11438.

Background: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa.  It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

Abbre: Mouse CD107a.

Buffer: PBS with 0.05% Proclin300, 1% BSA.

Clone No: 1D4B.

Conjugation: PE/Cyanine7 .

• Artikelnummer: ELSE-AB-F1254H-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-F1254H-100
• Verpackungseinheit: 100 Tests
• Mengeneinheit: PAK
• Reaktivität: Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: Rat IgG2a κ
• Human Gene ID: 16783
• Wirt: Rat