English
PerCP/Cyanine5.5 Anti-Human CD279/PD-1 Antibody(EH12.2H7), PerCP/Cy5.5, Mouse, Monoclonal
PerCP/Cyanine5.5 Anti-Human CD279/PD-1 Antibody(EH12.2H7), PerCP/Cy5.5, Mouse, Monoclonal
Artikelnummer
ELSE-AB-F1229J-200
Verpackungseinheit
100x2 Tests
Hersteller
Elabscience Biotechnology
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Swissprot: Q15116.
Background: Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Abbre: Human CD279/PD-1.
Buffer: PBS with 0.05% Proclin300, 1% BSA.
Clone No: EH12.2H7.
Conjugation: PerCP/Cyanine5.5.
Background: Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Abbre: Human CD279/PD-1.
Buffer: PBS with 0.05% Proclin300, 1% BSA.
Clone No: EH12.2H7.
Conjugation: PerCP/Cyanine5.5.
| Artikelnummer | ELSE-AB-F1229J-200 |
|---|---|
| Hersteller | Elabscience Biotechnology |
| Hersteller Artikelnummer | ELA-E-AB-F1229J-100X2 |
| Verpackungseinheit | 100x2 Tests |
| Mengeneinheit | PAK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Flow Cytometry |
| Human Gene ID | 5133 |
| Wirt | Mouse |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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