PERK (phospho Thr982) antibody

Application Note: WB: 1:1000-3000. ICC/IF: 1:100-500. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 125

Form: Liquid

Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]

Uniprot ID: Q9NZJ5

Antigen Species: Human

Immunogen: A synthesized peptide derived from human EIF2AK3(Accession Q9NZJ5), corresponding to amino acid residues around phosphorylated Thr 982.

Purification: Purified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Conjugation: Unconjugated

Full Name: eukaryotic translation initiation factor 2 alpha kinase 3

• Artikelnummer: GTX04533-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04533-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, ELISA, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 9451
• Wirt: Rabbit