Product Type: Inhibitor
CAS No.: 477575-56-7
MolecularFormula: C32H34Cl2N4O4S
Molecular Weight: 641,61
Source: Synthetic
Purity: >98
Solubility: Soluble to 100 mM in DMSO.
Appearance: Yellow solid
PubChem CID: 10461815
Scientific Background: PHA 665752 is a potent and selective MET kinase, ATP-competitive inhibitor. It has been studied as an antitumor agent because it has been seen to inhibit tumorigenicity and angiogenesis in mouse lung cancer xenografts.
References: 1. Puri N., Khramtsov A., Ahmed S., Nallasura V., Hetzel J., Jagadeeswaran R., et al. (2007) Cancer Res. 3529-34.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.