PI3 kinase C2 alpha antibody, C-term

Application Note: IHC-P: 5μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 191

Positive Control: The peptide used to generate this antibody is available for purchase (GTX89716-PEP).

Form: Liquid

Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.

Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]

Uniprot ID: O00443

Antigen Species: Human

Immunogen: Peptide with sequence C-TVKWYQLTAATYL, from the C Terminus of the protein sequence according to NP_002636.2.

Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation: Unconjugated

Full Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

• Artikelnummer: GTX89716-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX89716-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 5286
• Wirt: Goat