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PLN Polyclonal Antibody, Rabbit
PLN Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-93218-60
Verpackungseinheit
60 µl
Hersteller
Elabscience Biotechnology
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Abbreviation: PLN
Target Synonym: CMD1P;CMH18;PLB;PLN
Conjugation: Unconjugated
UNIProt ID: P26678
Background: The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human PLN
Dilution: WB 1:500-1:2000
Target Synonym: CMD1P;CMH18;PLB;PLN
Conjugation: Unconjugated
UNIProt ID: P26678
Background: The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human PLN
Dilution: WB 1:500-1:2000
| Artikelnummer | ELSE-AB-93218-60 |
|---|---|
| Hersteller | Elabscience Biotechnology |
| Hersteller Artikelnummer | ELA-E-AB-93218-60 |
| Green Labware | Nein |
| Verpackungseinheit | 60 µl |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine), Rat (Rattus) |
| Klonalität | Polyclonal |
| Methode | Western Blotting |
| Isotyp | IgG |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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