Poloppin, CAS 683808-78-8

Formulation: A solid

Formal Name: 5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrole-2-propanoic acid

Purity: ≥98%

Formula Markup: C20H15BrF3NO2

Formula Weight: 438,2

Shelf life (days): 1460

CAS Number: 683808-78-8

Notes: Poloppin is an inhibitor of the protein-peptide interaction between polo-like kinase 1 (Plk1) and the Plk1-binding phosphopeptide (IC50 = 26.9 µM).{64930} It induces mitotic arrest in HeLa cells (EC50 = 29.9 µM). Poloppin inhibits cell growth in murine pancreatic organoids expressing mutant K-Ras (GI50s = 22.92-28.39 µM).

• Artikelnummer: CAY38330-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38330-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe