Immunogen: Synthetic human gastrin I, conjugated to BSA
Concentration: n/a
Storage buffer: Lyophilized; reconstitute in 100 µl dist. water
Additional info: Gastrin-secreting cells are numerous in the antrum and a few are found in the proximal duodenum. The antibody can be used for the diagnosis of gastrin-producing tumors which are mainly found in the pancreas and occasionally in the stomach and the duodenum.
Absorption with 10-100 ug gastrin 1-34 and CCK 8 per ml antiserum abolishes the staining.Positive control: formalin-fixed paraffin sections of rat antrum.
References: Portela-Gomes, G. M.et al. Histochem. Cell Biol. 1999;111: 49–54 /Portela-Gomes, G. M.et al. J. Histochem. Cytochem.1997;45: 815–22 /Mulder, H. et al. Gastroenterology 1994;107: 712–9