Immunogen: Bombesin (#7113, Peninsula), conjugated to BSA
Concentration: n/a
Storage buffer: Lyophilized; reconstitute in 100 µl dist. water
Additional info: Bombesin is an amphibian peptide and the mammalian counterpart is referred to as Gastrin Releasing Peptide (GRP). Bombesin/GRP is widely distributed in the brain, in peripheral nerves (particularly numerous in the gut) and in endocrine cells of some sub-mammalian species, e.g. in the oxyntic mucosa of birds. The peptide stimulates secretion from endocrine and exocrine cells and intestinal smooth muscle activity. Bombesin/GRP occurs frequently in the bronchial carcinoids.
Absorption with 10-100 ug bombesin and GRP per ml diluted antiserum abolishes the staining.Positive control: formalin-fixed paraffin and frozen sections of rat or chicken stomach.