Polyclonal Rabbit anti-caspase-4 (N-Terminal)

Conjugate: Purified

Immunogen: A 16 amino acid peptide from human Caspase-4 amino terminus.

Concentration: 1.0 mg/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: Rabbit anti caspase-4 (N-terminal) antibody recognizes an epitope within the N-terminal region (NT) of Caspase-4, otherwise known as ICH-2. Caspase-4, a member of the Caspase-1 subfamily of cysteine proteases, exists as an inactive pro-enzyme which undergoes proteolytic cleavage of its p30 precursor form, into smaller p20 and p10 subunits.The cellular localization of Caspase-4 on the endoplasmic reticulum (ER) membrane, has resulted in this protein becoming a focus of studies in which dysfunction or stress to the ER membrane is implicated, such as Alzheimer’s disease and Ischemia and confirms the involvement of Caspase-4 as an instigator of cellular apoptosis.

• Artikelnummer: SANPS298
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: PS298
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Klonalität: Polyclonal
• Methode: Immunohistochemistry (paraffin), Western Blotting
• Wirt: Rabbit
• Konjugat: Conjugated