Polyclonal Rabbit anti-Mouse BLNK (SLP-65)

Immunogen: A fusion protein representing amino acids 171-356 of human BLNK.

Concentration: 1 mg/ml

Storage buffer: Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Additional info: SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa; B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins; thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.

• Artikelnummer: SANPS280
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: PS280
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Wirt: Rabbit
• Konjugat: Unconjugated