Target Synonym: Pro-opiomelanocortin;Corticotropin-lipotropin;NPP;Melanotropin gamma;Gamma-MSH;Potential peptide;Corticotropin;ACTH;CLIP;Alpha-MSH;Beta-LPH;Gamma-LPH;Beta-MSH;Beta-endorphin;Met-enkephalin
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: Pro-opiomelanocortin (POMC) is a precursor protein expressed in the pituitary and the brain where it is processed into several peptide hormones and neuropeptides. Among these peptides are ACTH,α- and β-MSH,β-and γ-LPH,CLIP,β-endorphin,and N-POMC. POMC is involved in hypothalamic circuits regulating feeding behavior and POMC-producing neurons promote satiety. POMC neurons are also the target of leptin and insulin for the promotion of the browning of white fat.
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
Immunogen: Synthetic peptide.
Dilution: WB 1:1000-1:2000
Calculated MW: 29 kDa
Observed MW: 35 kDa, 16 kDa
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