PRDM16 antibody

Application Note: WB: 1 μg/mL. IHC-P: 2-20 μg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 140

Form: Liquid

Buffer (with preservative): PBS, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Uniprot ID: Q9HAZ2

Antigen Species: Human

Immunogen: PRDM16 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16 (1120 - 1170).

Purification: Purified by antigen-affinity chromatography

Conjugation: Unconjugated

Full Name: PR/SET domain 16

• Artikelnummer: GTX03275-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX03275-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Immunohistochemistry (paraffin), Western Blotting, ELISA
• Isotyp: IgG
• Human Gene ID: 63976
• Wirt: Rabbit