PRMT6 Polyclonal Antibody, Rabbit

Abbreviation: PRMT6

Target Synonym: PRMT6;HRMT1L6

Conjugation: Unconjugated

UNIProt ID: Q96LA8

Background: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PRMT6

Dilution: WB 1:500-1:1000,IF 1:50-1:200

• Artikelnummer: ELSE-AB-92469-200
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92469-200
• Green Labware: Nein
• Verpackungseinheit: 200 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting
• Isotyp: IgG
• Wirt: Rabbit