Propargyl-PEG4-Tos, CAS 875770-32-4

Product Description: Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1][2]. Propargyl-PEG4-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C18H26O7S

References: [1]Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing ProteinDegradation. J Med Chem. 2018 Jan 25;61(2):453-461./[2]Senthilkumar T, et al. Conjugated Polymer Nanoparticles with Appended Photo-Responsive Units for Controlled DrugDelivery, Release, and Imaging. Angew Chem Int Ed Engl. 2018 Oct 1;57(40):13114-13119.

CAS Number: 875770-32-4

Molecular Weight: 386.46

Compound Purity: 95.41

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• Artikelnummer: MEXHY-130387-1G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130387-1G
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK