Product Description: PROTAC BTK Degrader-11 is a PROTAC degrader that can break down BTK, with a DC50 of 1.7 nM. PROTAC BTK Degrader-11 can be used in cancer research. (Pink: target protein ligand (HY-159956); Black: linker; Blue: E3 ligase (HY-150839))[1].
Applications: Cancer-Kinase/protease
Formula: C48H55N11O4
References: [1]Haitao Wang, et al. BGB-16673, A BTK Degrader, Overcomes On-Target Resistance From BTK Inhibitors And Present. FRANKFURT VIRTUAL. 2023. P1219.
CAS Number: 2736508-94-2
Molecular Weight: 850.02
Research Area: Cancer
Target: Btk;PROTACs