Product Description: PROTAC ERα Degrader-5 (compound LP2) consists an ADC linker and a PROTAC, whcih can be conjugated to an antibody to form PACs. PROTAC ERα Degrader-5 conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab)[1].
Applications: Cancer-programmed cell death
Formula: C94H107N13O16
References: [1]Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.
CAS Number: 2158322-33-7
Molecular Weight: 1674.93
Compound Purity: 98.96
Research Area: Cancer
Solubility: DMSO : 70 mg/mL (ultrasonic)
Target: Estrogen Receptor/ERR;PROTAC-Linker Conjugates for PAC