Formulation: A crystalline solid
Formal Name: 2-bromo-1-(4-hydroxyphenyl)-ethanone
Purity: ≥98%
Formula Markup: C8H7BrO2
Formula Weight: 215
Shelf life (days): 1460
CAS Number: 2491-38-5
Notes: PTP inhibitor I is an inhibitor of Src homology region 2 domain-containing phosphatase 1 (SHP-1) and protein tyrosine phosphatase 1B (PTP1B; Kis = 43 and 42 µM for the SHP-1 catalytic domain and full-length PTP1B, respectively).{31401} It inhibits endothelial cell network formation of human umbilical vein endothelial cells (HUVECs) cultured with normal human dermal fibroblasts (IC50 = 3.7 µM).{68464} PTP inhibitor I has been used in the synthesis of compounds with antibacterial, antifungal, fungicidal, and anticancer activities.{68465}