PTPN2 Polyclonal Antibody, Rabbit

Abbreviation: PTPN2

Target Synonym: PTPN2; PTN2; PTPT; TC-PTP; TCELLPTP; TCPTP; tyrosine-protein phosphatase non-receptor type 2

Conjugation: Unconjugated

UNIProt ID: P17706

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PTPN2

Dilution: WB 1:500-1:2000,IF 1:50-1:200

• Artikelnummer: ELSE-AB-93348-200
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-93348-200
• Green Labware: Nein
• Verpackungseinheit: 200 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting
• Isotyp: IgG
• Wirt: Rabbit