Target Synonym: Neprilysin;Atriopeptidase;CALLA;Enkephalinase;NEP;Neutral endopeptidase;Skin fibroblast elastase;SFE;CD10;
Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Background: CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.
Buffer: Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
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